St. John's Wort (Hypericum perforatum) is an herbal remedy commonly used for mild to moderate depression.
300 mg standardized extract (0.3% hypericin), three times daily.
Strong evidence from multiple high-quality studies.
Methodology
Cochrane review
Participants
0 subjects
Key Outcomes
Confirmed effectiveness for mild to moderate depression across 29 trials
Linde et al. (2008)
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Methodology
Randomized controlled trial
Participants
332 subjects
Key Outcomes
Comparable efficacy to standard antidepressants
Kasper et al. (2006). BMJ
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Methodology
Meta-analysis
Participants
0 subjects
Key Outcomes
Confirmed efficacy and safety profile
Ng et al. (2017). Journal of Affective Disorders
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Disclaimer: This information is for educational purposes only and not intended as medical advice. Please consult with a healthcare professional before taking any supplements, especially if you have underlying health conditions or are taking medications.